この成果によりCyanine系の蛍光色素に任意の長さのPEGをアミド結合などを介さず直接結合できる目途が立ちました。
より長いPEG鎖の結合、カルボン酸以外の末端構造の合成も検討を進めています。一般の受託合成、特注合成とは異なる価格帯でご希望の構造に対応致しますのでお気軽にお問い合わせください。
これまでの合成実績の幾つかをご紹介します。（構造式を
）
| SCHEM No. | Structure | Compound Name | Price (JPY) | Purity | Stock(mg) |
|---|---|---|---|---|---|
| 02138 |  | Trt-PEG135-OBz(3,5-NO2) | 119,600/0.1mg | >80% | 0.1 |
| 05950 |  | Sulforhodamine bis(CO-PEG14-COOH) | 64,600/0.1mg | >95% | 1.6 |
| 05187 |  | BODIPY-4-O-PEG13-COOtBu | 64,600/0.1mg | >95% | 3.0 |
| 02138 | | Trt-PEG135-OBz(3,5-NO2) | 119,600/0.1mg | >80% | 0.1 |
| 04621 |  | OH-PEG27-O-BODIPY | 65,300/0.4mg | >90% | 0.1 |
| 04516 |  | DMT-PEG27-O-4-BODIPY | 63,100/0.6mg | >90% | 12.2 |
| 02139 |  | Trt-PEG27-Bz(3,5-NO2) | 63,100/0.6mg | >90% | 2.5 |
| 02140 |  | Trt-PEG18-Bz(3,5-NO2) | 63,100/0.6mg | >95% | 1.2 |
| 05950 | | Sulforhodamine bis(CO-PEG14-COOH) | 64,600/0.1mg | >95% | 1.6 |
| 06798 |  | Cy5(1-PEG3-OMe 5-SO3H 8,8-diMe 1'-PEG13-COOH 8',8'-diMe) | 119,600/0.1mg | >95% | 0.1 |
| 06461 |  | Cy5(PEG3-OMe)(PEG13-COOtBu) | 119,600/0.1mg | >95% | 0 |
| 06410 |  | Cy7(1-PEG13-COOH 5-SO3H 8,8-diMe 1'-PEG3-OMe 5'-SO3H 8',8'-diMe) | 119,600/0.1mg | >95% | 0.4 |
| 06064 |  | Cy7(1-HexCONH-PEG13-COOtBu 5-SO3H 8,8-diMe 1'-Et-SO3H 8',8'-diMe) | 96,000/0.1mg | >95% | 0 |
| 05373 |  | Cy5(1-Pr-SO3H 5-SO3H 8-Me 8-Hex-CONH-PEG13-CONH-PEG2-Hex-Cl 1'-Pr-SO3H 5'-SO3H 8',8'-diMe) | 119,600/0.1mg | >90% | 0.1 |
| 05187 | | BODIPY-4-O-PEG13-COOtBu | 64,600/0.1mg | >95% | 3.0 |
| 05078 |  | Cy5(1-Pr-SO3H 5-SO3H 8-Me 8-Hex-CONH-PEG13-COOtBu 1'-Pr-SO3H 5'-SO3H 8',8'-diMe) | 96,000/0.1mg | >90% | 0 |
| 04959 |  | BODIPY-4-O-PEG13-COOH | 96,000/0.1mg | >95% | 0.1 |
| 04746 |  | CF660R-PEG13-PEG2-O-HexCl | 119,600/0.1mg | >95% | 0.1 |
| 04731 |  | DY-547-CONH-PEG13-COOH | 69100/<0.1mg | >95% | 0.1 |
| 04730 |  | Texas-Red-X-CONH-PEG13-COOH mixed isomers | 69100/<0.1mg | >95% | 0.1 |
| 04729 |  | BODIPY FL C5-CONH-PEG13-COOH | 69100/<0.1mg | >95% | 0.1 |
| 04728 |  | 5(6)-TAMRA-CONH-PEG13-COOH | 69100/<0.1mg | >95% | 0.1 |
| 04727 |  | Cy3-CONH-PEG13-COOH | 64,600/0.1mg | >95% | 0.1 |
| 04726 |  | Cy5(1-Hex-CONH-PEG13-COOH 8,8-diMe 1'-Me 8',8'-diMe) | 69100/<0.1mg | >90% | 0.1 |
| 04722 |  | 5(6)-TAMRA-CONH-PEG13-COOtBu | 64,600/0.1mg | >95% | 0.1 |
| 04721 |  | Cy3-CONH-PEG13-COOtBu | 72,400/0.2mg | >95% | 0.1 |
| 04720 |  | Cy5(1-Hex-CONH-PEG13-COOtBu 8,8-diMe 1'-Me 8',8'-diMe) | 72,400/0.2mg | >90% | 1.5 |
| 06479 |  | Cy5(1-PEG12-OMe 5-SO3H 8,8-diMe 1'-AcOtBu-8',8'-diMe | 64,600/0.1mg | >90% | 0.4 |
| 06518 |  | Cy5(1-Hex-COOH 5-SO3H 8,8-diMe 1'-Et 5'-SO3H 8'-Me 8'-PEG11-OMe | 64,600/0.1mg | >90% | 0 |
| 06402 |  | Cy7(1-HexCOOH 5-SO3H 8,8-diMe 1'-PEG10-OAc 5'-SO3H 8',8'-diMe) | 64,600/0.1mg | >95% | 0 |
