macrocyclic crown ether

Macrocyclic polyethers were synthesised by applying Shinsei Chemical's unique single structure polyethylene glycol synthesis technology.

As 18-Crown-6 is widely used as a correlation transfer catalyst and host-guest compound, polymeric cyclic ethers are also reported to perform well as polymeric materials and as modifiers in lithium-ion batteries.
We have succeeded in synthesising a single structure, giant crown ether by intramolecular cyclisation of polymeric PEG obtained by our unique synthetic method.
At present, the largest molecular weight synthesis has been achieved with a molecular weight of 4,934 (repeat unit 112: 336-Crown-112), but further macrocyclic structures can also be synthesised as the synthesis method has already been established.









Comparison sample: cyclic ether (SCHEM00927) derived from commercially available PEG (molecular weight distribution with average molecular weight 2,000): the chromatogram appears to be a single peak, but the MS spectrum clearly shows that it is a mixture of about 37 to 46 repeat units.



Shinsei Chemical has a large number of synthesised products, such as branched PEG derivatives and poly-THF, using high-purity polyether synthesis technology.


Branched crown ether technical data.
Cyclic PEGs with disulphide bonds.
S-containing crown ether
Azacrown ether (N-containing crown ether)
List of crown ethers

We have experience in the derivation of various functional groups by applying single-structure PEG synthesis technology.

PEG-related technical documents

• Mono-disperse polyethylene glycols(TD001)
• PEG hybrid compounds(TD025)
• PEG linker that can be cleaved under mild conditions(TD030)(not ready)
• macrocyclic crown ether(TD034)
• Fluorescently labelled PEG molecular weight markers(TD036)
• Crown ether with branches(TD037)
• Cyclodextrins with PEG linkers(TD042)
• Synthesis of dyes with PEG linkers and fluorescent dyes(TD048)
• Functionalisation of each end of PEG Linker(TD049)
• Spacers and cross-linkers(TD050)
• PEG dicarboxylic acid derived from commercial PEG(TD054)
• Diamino PEG derived from commercial PEG(TD055)
• HaloTag HaloLinker (HaloTag HaloLinker)(TD066)
• List of PEG derivatives
• List of fluorescently labelled PEG derivatives

Click herefor any Orgenic compounds.