We do not compromise on quality even with low-cost non-monodisperse PEG derivatives with molecular weight distribution.
We are promoting monodispersepolyethylene glycol (PEG), which has a single structure with no molecular weight distribution, but it requires multi-step synthesis and so it is not easy to reduce the cost significantly. Unfortunately, some customers are reluctant to use our high purity PEG derivatives because of the high price.
Keeping costs down is a priority and molecular weights do not have to be the same....We get a lot of inquiiries about derivatives using cheaper commercial PEG as the starting material.
Although cheaper than single-structure PEG, it still requires advanced technology when it comes to high quality. There is expertise in refining low purity materials.
Separation of target carboxylic acids and amines from unreacted OH groups by ion-exchange resin methods or medium-pressure reversed-phase columns becomes significantly more difficult as molecular weight increases.
Separation of isomers with different repeating units becomes impossible as molecular weight increases, but other impurities and unreacted OH group structures can be separated with some ingenuity. Shinsei Chemical uses proprietary methods to thoroughly remove impurities other than the target product, unreacted raw materials and over-reaction structures, and provides PEG derivatives of the highest possible purity.
We use protective groups to significantly change the polarity and remove the unreacted OH-body completely before removing the protective groups, resulting in a structure with functional groups at both ends.
Click on the SCHEM No. in the list to display a detailed page.
SCHEM No. | Structure | Compound Name | Price (JPY) | Purity | Stock(mg) |
---|---|---|---|---|---|
01990 | NH2-PEG2K-NH2 | 78,800/10mg | <80% | 205.2 | |
01992 | NH2-PEG1.4K-NH2 | 81,900/25mg | <80% | 128.7 | |
06099 | NH2-PEG1K-NH2 | 81,900/50mg | <80% | 837.4 |
Other structures, not listed here, with different average molecular weights or other functional groups are also available.