Glucuronide conjugates
We have established methods for the synthesis of a variety of glucuronic acid conjugates.
Fat-soluble toxicants are known to bind to glucuronic acid to form metabolites in order to increase their polarity and eliminate them from the body,
and there is a need for standard products to analyse these metabolites. Various glucuronic acid conjugates can be synthesised.
Glutathione conjugates and sulphate conjugates have also been synthesised. Compounds not listed may be available at similar prices.
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| SCHEM No. | Structure | Compound Name | Price (JPY) | Purity | Stock(mg) |
|---|---|---|---|---|---|
| 08717 |  | Diethyl stilbestrol glucuromide | 65,000/0.2mg | >95% | 2.8 |
| 08716 |  | Dienestrol glucuronide | 95,000/0.2mg | >95% | 2.1 |
| 08631 |  | Hexesterol gluruconide | 65,000/0.2mg | >95% | 2.0 |
| 07643 |  | 2-methylimidazole glucuronide | 64,000/0.7mg | >80% | 1.6 |
| 07639 |  | 2-nitroidazole glucuronide | 65,000/1mg | >95% | 3.7 |
| 07633 |  | 2-n-butylimidazole glucuronide | 65,000/1mg | >95% | 9.5 |
| 07629 |  | 2-n-butylimidazole glucuronide | 64,900/7.5mg | >95% | 20.2 |
| 07626 |  | 4-Chlorophenol glucuronide Methylester triacetate | 64,900/7.5mg | >95% | 0 |
| 07594 |  | 2,4,5-Trichlorophenol 1-glucuronide | 65,000/1mg | >95% | 5.8 |
| 07586 |  | 2-Nitroimidazole glucuronide Methylester triacetate | 65,000/5mg | >95% | 75.6 |
| 07580 |  | 4-Chlorophenol 1-glucuronide | 64,500/0.8mg | >95% | 1.9 |
| 07547 |  | 2,3,4,5-Tetrachloro-2-methoxy 1-glucuronide | 64,000/0.7mg | >95% | 0 |
| 07543 |  | 4-Bromophenol 1-glucuronide | 65,000/1mg | >95% | 3.1 |
| 07118 |  | 2,4-Dichlorophenol 1-glucuronide-D3 | 65,700/0.4mg | >95% | 0 |
| 07111 |  | 2,4,6-Trichlorophenyl-1-glucuronide | 66,300/2.5mg | >95% | 0 |
| 07110 |  | 2,4,6-Trichlorophenyl-2,3,4-triacetyl-1-glucuronide methyl ester | 68,800/5mg | >95% | 0 |
| 06899 |  | Dexmedetomidine glucuronide | 65,000/1mg | >95% | 1.4 |
| 06896 |  | 2,4,5-Triphenol glucuronide Methylester triacetate | 68,800/5mg | >95% | 42.0 |
| 05865 |  | 3-methyl-4-nitrophenol glucuronide | 65,000/1mg | >95% | 18.8 |
| 05848 |  | 5-phenyl-isoxazol-3-ol glucuronide | 65,000/1mg | >95% | 3.6 |
| 05839 |  | 2,4-Dichlorophenol glucuronide | 65,000/1mg | >95% | 7.0 |
| 05835 |  | 2,4-Dichlorophenol glucuronide Methylester triacetate | 30,000/5mg | >95% | 35.3 |
| 05767 |  | Valproic acid acyl glucuronide | 65,000/1mg | >95% | 47.0 |
| 05758 |  | (S)-Naproxen Acylglucuronide | 65,000/2mg | >95% | 114.0 |
| 05757 |  | ibuprofen acyl glucuronide | 65,000/1mg | >95% | 102.0 |
| 05756 |  | Mefenamic acid acyl glucuronide | 65,000/1mg | >95% | 86.0 |
| 05755 |  | Diclofenac acyl glucuronide | 65,000/1mg | >95% | 20.0 |
| 05746 |  | (2S)-naproxen acyl glucronide benzyl ester | 65,000/5mg | >95% | 369.0 |
| 05744 |  | Mefenamic acid acyl glucuronide benzyl ester | 65,000/1mg | >95% | 100.0 |
| 05743 |  | Diclofenac acyl glucuronide benzyl ester | 65,000/1mg | >95% | 74.0 |
| 05682 |  | Carprofen acy glucuronide,benzyl ester | 65,000/1mg | >95% | 83.0 |
| 05677 |  | Benzyl alpha,beta-D-glucuronate | 68,100/750mg | >90% | 1,728.0 |
| 05672 |  | 1,2,3,4-Tetra-O-acetyl-beta-D-glucuronic acid allyl ester | 63,400/5mg | >90% | 60.0 |
| 05621 |  | Acetobromo-alpha-D-glucuronic acid methyl ester | 12,000/1,000mg | >90% | 13,081.4 |
| 05434 |  | Chloramphenicol glucuronide tetracetate methylester | 68,100/0.2mg | >95% | 78.8 |
| 05293 |  | Chloramphenicol 3-O-beta-D-Glucuronide | 40,000/1mg | >95% | 2.7 |
| 01589 |  | 2-Methylimidazole glucuronide Methylester triacetate | 50,000/1mg | >95% | 0 |
Compounds not listed may be available at similar prices. If the structure has only different substituents, the synthesis method has already been established, so it takes 1-2 weeks and can be synthesised in the same level price range.
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